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The Fuction of Vitamin D in daily life

A new study shows that vitamin D3 can help women shape muscles and reduce the loss of muscle mass, and even maintain muscles for more than ten years after menopause. There has been new progress in the debate about how vitamin D helps postmenopausal women. A recent Brazilian study showed that women who take vitamin D have increased their muscle strength by 25%.

This study was presented at the Las Vegas North American Menopause Academic Conference 2015.

Researchers in São Paulo conducted a nine-month, double-blind, placebo-controlled study. They measured the muscle mass of the subjects using the whole DXA method (dual energy X-ray absorptiometry) and measured the handle strength with a weight test.

At the end of the experiment, the muscle strength of the female subjects who took supplements increased by 25.3%, while that of the female subjects who took placebos decreased by an average of 6.8%. The decrease in muscle mass of women who did not take vitamins was twice that of women taking vitamins.

Dr. Cangussu, a professor at the University of Sao Paulo’s Botucatu Medical School and also a leader of the study, said: “It can be seen from our research that vitamin D supplementation alone can reduce the degree of muscle loss. Muscle loss is a degenerative loss of skeletal muscle. "

Vitamin D also plays a vital role in eye health, especially in the prevention of age-related maculopathy, which is often caused by the impairment of vision due to genetic predisposition in women.

In a paper published in the JAMA Eye Online journal on August 27th, Dr. Millen and associates of the Department of Epidemiology and Environmental Health at the Buffalo University School of Public Health and Health found that the lack of vitamin D and high Women with a genotype of risk were 6.7 times more likely to have macular degeneration than normal women.

Dr. Millen said: "Most people have heard that eating radish can help our eyesight. But there are other ways to support eye health by taking enough nutrients. Supplementing enough vitamin D is just one of them. This is not a causal relationship that can be demonstrated by a single study. However, the results of the study tell us that if you are a high-risk genotype of maculopathy, taking enough vitamin D may help reduce the risk of the disease."

 She added: "Based on our experience, this is the first study to explore the relationship between genetic risk and vitamin D status in age-related eye diseases."

The researchers analyzed data from 1,230 women (aged 54 to 74 years) who participated in the age-related eye disease study of carotenoids. This study was a supplementary study of the women's health initiative's observational study.

Researchers can determine the vitamin D status of a subject by analyzing the vitamin D biomarker (hydroxyergosterol) in serum samples.

 When we are exposed to ultraviolet light, human skin can synthesize vitamin D. However, it is sufficient to have 10% of the skin exposed to ultraviolet rays every day for 15 to 30 minutes. In the winter, the sun shines at a low angle for people living north of the parallel lines in Washington, DC and Los Angeles. The degree of exposure to sunlight may not be sufficient to maintain the blood level of vitamin D. Therefore, dietary intake is needed. Dietary sources of vitamin D include fortified foods (such as milk) and vitamin D naturally occurring foods (such as salmon and mackerel).

Inflammation is present in the development of maculopathy. Vitamin D can prevent maculopathy because of its anti-inflammatory and anti-angiogenic properties. Anti-angiogenesis means slowing the growth of new blood vessels, and this phenomenon usually occurs late in macular degeneration.

Dr. Millen said: “Our conjecture is that if a person's vitamin D status is good, then does it reduce the immune response of choroidal diaphragmatic? We would like to know if the difference between vitamin D and macular degeneration depends on a person. The risk of genotypes of macular degeneration. Our study showed that the lack of vitamin D increases the risk of macular degeneration, and this increased risk may have a profound effect on the specific variants of the complement factor proteins that have the highest genetic risk."

Dr. Millen also said: "This study supports the role of vitamin D in eye health, which is very important because of the study published by the Medical Association in 2011 on dietary intake of vitamin D and calcium. Only conclusions about the relationship between vitamin D and bone health have been made. At that time, there was not enough evidence to prove that the state of vitamin D and its products are helpful to any tissues other than bone."

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