Benepure 青益纯医药
Media and Communications
Professional \ Focused \ Dedicated

Your location:Home > Information and Dynamic

Soy Isoflavones: Are They Useful in Menopause?

In October 1999, the US Food and Drug Administration authorized the use on food labels of health claims associated with soy protein and the reduced risk of coronary heart disease. Several studies have indicated that a total daily intake of 25 g of soy protein paired with a low-fat diet resulted in clinically important reductions of total cholesterol and low-density lipoprotein (LDL) cholesterol levels. Soybeans are a rich source of isoflavones, a class of phytoestrogens found predominantly in legumes and beans. Soy isoflavones are heterocyclic phenols with structural similarity to estradiol-17β and selective estrogen receptor modulators.

Actions at the cellular level depend on the target tissue, receptor status of the tissue, and the level of endogenous estrogen. Studies of soy-based diets evaluating the relation between soy consumption and serum lipid concentrations revealed that soy consumption significantly decreased total cholesterol, LDL cholesterol, and triglyceride levels. However, the soy isoflavones do not increase high-density lipoprotein cholesterol or triglyceride levels.


Thus far, there is no evidence for a stimulatory effect of isoflavones on the endometrium. A few studies reveal a minimal effect of soy on hot flashes, with soy reducing hot flashes 45% and placebo causing a 30% re duction compared with an approximate 70% reduction in hot flashes with estrogen replacement therapy. Evidence from laboratory studies reveals neither a positive nor a negative effect of soy isoflavones on cognition. To date, no adverse effects of short- or long-term use of soy proteins are known in humans. The only adverse effects known are those reported in animals (infertility in sheep and quails grazing on phytoestrogen-rich pastures).

In conclusion, soy isoflavones are biologically active compounds. Current data are insufficient to draw definitive conclusions regarding the use of isoflavones as an alternative to estrogen for hormone replacement in postmenopausal women. Although epidemiological and basic laboratory studies allude to the possible protective effects of soy isoflavones at specific target tissues, randomized, placebo-controlled clinical trials are necessary to address these important issues.


Sichuan Benepure Pharmaceutical Co.,Ltd. Is specialized in botanical extracts, includes Soy Isoflavones, which is sourced from the natural plant Phellodendron amurense and Berberis sargentiana. The material Berberine has been export by Benepure to many countries abroad. If any needs, please feel free to contact with us.

Soy Isoflavones

Phone: +86 28 8679 9990

Email: sales@benepure.com




Previous: The Fuction of Vitamin D in daily life

Next: What is Neohesperidin dihydrochalcone?



WHAT WE DO HOW WE DO WHO WE ARE CONTACT US

FOLLOW US

Facebook
Twitter
Linkedln
Skype
TencentQQ
SinaWeibo
Wechat
Botanical Extracts API Intermediates Food & Nutrition Flavors & Pigments Amino acid & Derivatives Oem & Souring Why Choose Us Innovation & Technology Quality and Service Industry Chain About Us R&D Center Production Contact Us Join Us
Tel:+86 28 8679 9990   +86 28 8679 8880
Fax:+86 28 8679 9924
Email: info@benepure.com
Address:99# Jirui 3rd Road, High-tech District,Chengdu, Sichuan Prov., China 610095
   
Privacy protection 
Copyright ©2010-2016 BENEPURE Corporation, All Rights Reserved