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Yohimbine HCL


Yohimbine HCL Product Name: Yohimbine HCL (Yohimbine Hydrochloride)

Specification:98.0%

Test Method: HPLC

CAS:  65-19-0

Molecular Formula: C21H27ClN2O

Molecular Weight: 254.23

Constitutional Formula:

Yohimbine HCL

Efficacy: Vasodilator, Aphrodisiac

Botanical Source: Pausinystalia yohimbe

Sources and Habitat:

Yohimbe is a tall evergreen forest tree, reaching a height of 90 feet and width of 40 feet, native to southwestern Nigeria, Cameroon, Gabon, and the Congo.

The material of commerce is collected in the wild in this same region.Yohimbe bark consists of the dried bark of the trunk and branches of Pausinystalia yohimbe (K. Schumann) Pierre ex Beille [syn. Corynanthe yohimbi Schumann] [Fam. Rubiaceae] and its preparations. The bark contains alkaloids. The main alkaloid is yohimbine.

Indications and Uses:

Yohimbine hydrochloride is indicated as a sympathicolytic and mydriatic. It may have activity as an aphrodisiac.Impotence (not able to have erections).The way yohimbine works is not known for sure. It is thought, however, to work by increasing the body's production of certain chemicals that help produce erections.

It does not work in all men who are impotent.New research that shows it could be an herb with very effective antioxidant potential.

Research shows it is a vasodilator, which means that it increases blood flow to the extremities and appendages.

Safety Concerns:

Patients sensitive to rauwolfia alkaloids such as deserpidine, rauwolfia serpentina, or reserpine may also be sensitive to yohimbine.

Yohimbine readily penetrates the (CNS) and produces a complex pattern of responses in lower doses than those required to produce peripheral alpha-adrenergic blockade. These include, antidiuresis, a general picture of central excitation including elevation of blood pressure and heart rate, increased motor activity, nervousness, irritability and tremor. Sweating, nausea and vomiting are common after parenteral administration of the drug. Also, dizziness, headache skin flushing reported when used orally.Generally, this drug is not proposed for use in females and certainly must not be used during pregnancy. Neither is this drug proposed for use in pediatric, geriatric or cardiorenal patients with gastric or  duodenal ulcer history. Nor should it be used in conjunction with mood modifying drugs  such as antidepressants ,  or in psychiatric patients in general.

Renal diseases and patient's sensitive to the drug. In view of the limited and inadequate information at hand, no precise tabulation can be offered of additional contraindications.

It is important that your doctor check your progress at regular visits to make sure that this medicine is working properly.

Use yohimbine exactly as directed by your doctor. Do not use more of it and do not use it more often than ordered. If too much is used, the risk of side effects such as fast heartbeat and high blood pressure is increased.

Dosage Information:

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine.

If your dose is different, do not change it unless your doctor tells you to do so.The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


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