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Diosmin- Dosage and how to take

Diosmin is available over the counter in the United States, Canada, and certain European countries. It’s typically sold as micronized purified flavonoid fraction (MPFF), which usually contains 90% diosmin and 10% hesperidin.

The most common and well-researched supplement is Daflon 500 (450 mg diosmin, 50 mg hesperidin). It’s also known as Detralex in some regions. However, many other diosmin products are likely available in your local pharmacy and online.

Most diosmin products recommend taking one 500-mg supplement with food once in the morning and again in the evening for a total of 1,000 mg per day.

Under the guidance of a health professional, these dosage guidelines have been shown to be safe and effective for various conditions:

Chronic venous disease: 1,000 mg per day for 3–6 months
Hemorrhoids: 1,000–2,000 mg per day for 4 days, followed by 1,000 mg per day for 3 days
Varicose veins: 1,000–2,000 mg per day for up to 6 months

Do not take diosmin for more than 3 months — or take more than the recommended dose on the label — unless instructed by your healthcare provider.


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