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Micronized purified flavonoid fraction for the treatment of chronic venous insufficiency



MPFF is composed of micronized diosmin and flavonoids. Its flavonoid fraction can take many forms, including that of hesperidin, diosmetin, and linarin.The proportion of micronized diosmin to flavonoids varies, with 9:1 being a commonly used ratio. MPFF acts on improving venous obstruction, valvular reflux, and inflammatory venous damage, which are key components contributing to the pathogenesis of PTS. MPFF is a good candidate to explore as a potential therapy for PTS.



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