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Patent application for key techniques of Cepphalotaxine



Benepure has recently submitted its patent application to National Intellectual Property Division.

Product Name: Cephalotaxine

Synonym: Cephalotoxin, Cephatotoxin

Cephalotaxine, naturally in the stems of Cephalotaxine plant genera, belongs to one of alkaloids. Cephalotaxus fortunei Hook.f. origins from China, spreading over southern region of Yangtze River, Hubei, Sichuan, Shanxi and Gansu provinces. Its fruits are used to help digestion and expel pests in folk. The curative effect of antitumor, particularly Chronic Myeloid Leukaemia is significant.

Number:BPAPI-41

Specification:HPLC≥98%

CAS: 24316-19-6

MF&MW:C18H21NO4;315.36

Appearce: white to off-white or white to faint yellow solid.

Physical Property

Melting Point: 132℃-133℃; Specific Rotation: (c, 1.8 in CHCl3)-204, generate crystalline salt with hydrochloric acid and perchloric acid; turn to be royal purple from red met with oil of vitriol and green solution in water.



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