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Citrimore is formed for citrus extracts and their derivatives. Through decades' in-depth study on various of citrus in different places of origin, we obtain a clear understanding inf Citrus.



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Diosmetin


Diosmetin Product Name: Diosmetin

Synonym: 3',5,7-Trihydroxy-4'Methoxyflavone

CAS Number: 520-34-3

Specification: 97%,98%HPLC

Raw material main source: Sichuan, Jiangxi, Zhejiang, Guangxi, Hunan, etc.

Appearance: Yellow fine powder

Botanical Source: Citrus limon L.

Application:

Diosmetin is an O-methylated flavone found in vetch and various citrus fruits; it exhibits antioxidative, anti-inflammatory, and anti-osteoporotic activities. In animal models of AAPH-induced oxidative stress, diosmetin decreases generation of ROS and increases levels of superoxide dismutase, catalase, and glutathione peroxidase. Diosmetin also decreases amylase, lipase, TNF-α, IL-1β, IL-6, and iNOS in animal models of pancreatitis. Additionally, this compound increases activation of PKC, ERK1/2, and p38 MAPK, inducing osteoblastic differentiation in vitro.


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